Chemical peel, also known as chemexfoliation or chemical exfoliation, is a procedure where a chemical substance applied to the skin causes controlled destruction of the epidermis with or without part of the dermis, leading to skin regeneration and remodeling.(5,7)
Chemical peels can be used to treat various skin conditions, such as acne vulgaris, photodamage, pigmentary disorders, and scars.
Chemical Peel consists in the application of one or more chemical substances, in immediate or delayed sequence, able to induce the destruction of epidermal areas and/or layers of the dermis and the subsequent tissue regeneration process, to treat some skin conditions and/or resolve or improve the clinical-aesthetic aspects.(5,7)
The effects of the chemicals range from simple detachment of the corneum layer to considerable inflammatory reactions of the dermis; they depend on various factors and on some variables, able to determine the uniformity of the penetration effect, the levels of attainable depths and a more or less marked exfoliative reaction.(1)
Chemical peels are commonly classified based on their depth of skin penetration into superficial, medium, and deep peels.
The factors affecting the depth of peeling, and thus the degree of its therapeutic effects, include the properties of the chemical agent used (e.g., concentration and pH), the physician’s application technique, and the patient’s skin condition and sensitivity.(7)
When performing a chemical peel, proper patient evaluation, and execution of a comprehensive treatment plan can produce safe, reliable, and satisfactory outcomes.
Various indications for using chemical peeling as a technique for skin resurfacing exist, including:(8,11)
- Facial rejuvenation of the aging skin to address issues such as enlarged pores and rhytides
- Inflammatory disorders including acne vulgaris, pseudofolliculitis barbae, rosacea, and post-acne scarring
- Pigmentary disorders such as melasma, ephelides or freckles, lentigines, and post-inflammatory pigmentation
- Epidermal proliferation and pre-cancerous lesions including sebaceous and actinic keratosis